DEDD antibody (AA 151-250) (Cy3)

Catalog No. ABIN893808

Product Details anti-DEDD Antibody (Cy3)

Target: DEDD (Death Effector Domain Containing (DEDD))

Binding Specificity: AA 151-250

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DEDD antibody is conjugated to Cy3

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity: Human, Rat

Predicted Reactivity: Mouse,Cow,Pig,Chicken

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human DEDD1

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for DEDD

Target: DEDD (Death Effector Domain Containing (DEDD))

Alternative Name: Dedd1 (DEDD Products)

Synonyms: CASP8IP1 antibody, DEDD1 antibody, DEFT antibody, FLDED1 antibody, Dedpro1 antibody, KE05 antibody, Deft antibody, death effector domain containing antibody, death effector domain-containing antibody, DEDD antibody, Dedd antibody

Background:

Synonyms: DEFT, KE05, DEDD1, FLDED1, CASP8IP1, Death effector domain-containing protein, DEDPro1, Death effector domain-containing testicular molecule, FLDED-1, DEDD

Background: A scaffold protein that directs CASP3 to certain substrates and facilitates their ordered degradation during apoptosis. May also play a role in mediating CASP3 cleavage of KRT18. Regulates degradation of intermediate filaments during apoptosis. May play a role in the general transcription machinery in the nucleus and might be an important regulator of the activity of GTF3C3. Inhibits DNA transcription in vitro (By similarity).

Gene ID: 9191

UniProt: O75618