DBF4 antibody (AA 21-110) (Biotin)

Catalog No. ABIN893544

Product Details anti-DBF4 Antibody (Biotin)

Target: DBF4 (DBF4 Homolog (DBF4))

Binding Specificity: AA 21-110

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DBF4 antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Predicted Reactivity: Human,Mouse,Rat,Cow,Sheep,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human DBF4A

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for DBF4

Target: DBF4 (DBF4 Homolog (DBF4))

Alternative Name: DBF4A (DBF4 Products)

Synonyms: ASK antibody, CHIF antibody, DBF4A antibody, ZDBF1 antibody, RGD1305854 antibody, DBF4 antibody, LOC100229596 antibody, AA545217 antibody, Ask antibody, dbf4a antibody, xdbf4 antibody, ChDBF4 antibody, DBF4 zinc finger antibody, DBF4 zinc finger L homeolog antibody, DBF4 antibody, dbf4 antibody, Dbf4 antibody, dbf4.L antibody

Background:

Synonyms: Activator of S phase kinase, ASK, Chfon homolog A, DBF4, DBF4 type zinc finger containing protein 1, DBF4-type zinc finger-containing protein 1, DBF4A, DBF4A_HUMAN, Protein DBF4 homolog A, ZDBF1.

Background: Regulatory subunit for CDC7 which activates its kinase activity thereby playing a central role in DNA replication and cell proliferation. Required for progression of S phase. The complex CDC7-DBF4A selectively phosphorylates MCM2 subunit at 'Ser-40' and 'Ser-53' and then is involved in regulating the initiation of DNA replication during cell cycle.Tissue specificity: Highly expressed in testis and thymus. Expressed also in most cancer cells lines.

Gene ID: 10926

Pathways: Mitotic G1-G1/S Phases, DNA Replication