CSMD2 antibody (AA 251-350) (Biotin)

Catalog No. ABIN892435

Product Details anti-CSMD2 Antibody (Biotin)

Target: CSMD2 (CUB and Sushi Multiple Domains 2 (CSMD2))

Binding Specificity: AA 251-350

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CSMD2 antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Dog,Cow,Sheep,Horse,Chicken

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CSMD2

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for CSMD2

Target: CSMD2 (CUB and Sushi Multiple Domains 2 (CSMD2))

Alternative Name: CSMD2 (CSMD2 Products)

Synonyms: CUB antibody, CSMD antibody, sushi antibody, si:bz1c3.1 antibody, dJ1007G16.1 antibody, dJ1007G16.2 antibody, dJ947L8.1 antibody, B230311I21 antibody, B230378I17 antibody, Gm139 antibody, mKIAA1884 antibody, RGD1565728 antibody, CUB and Sushi multiple domains 2 antibody, CUB and sushi domain-containing protein 2 antibody, CSMD2 antibody, csmd2 antibody, LOC100069927 antibody, LOC100542920 antibody, LOC100563756 antibody, Csmd2 antibody

Background:

Synonyms: CSMD2, CSMD2_HUMAN, CUB and Sushi SCR repeat domain, CUB and sushi domain-containing protein 2, CUB and sushi multiple domains protein 2, dJ1007G16.1, dJ1007G16.2, dJ947L8.1, KIAA1884.

Background: The CUB and sushi domain-containing proteins, CSMD1-3, are membrane proteins that are involved in cell-cell adhesion and are weakly expressed in most tissues, with higher levels of expression observed in the cerebellum and hippocampus. CSMD1 is part of the complement system that defends against pathogens through either the classical pathway or the alternative pathway. Located primarily in nerve growth cones, CSMD1 blocks the classical pathway of the immune system and is thought to be involved in tumor suppression, as defects in the gene encoding CSMD1 are associated with squamous cell carcinomas. CSMD2 and CSMD3 are located primarily in the brain and are implicated in some forms of head and neck cancer. Additionally, the CSMD3 gene is a candidate for induction of epileptic seizures.

Gene ID: 114784