Corin antibody (AA 165-245) (Biotin)

Catalog No. ABIN891975

Product Details anti-Corin Antibody (Biotin)

Target: Corin (CORIN) (Corin, Serine Peptidase (CORIN))

Binding Specificity: AA 165-245

Reactivity: Human, Rat, Sheep

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Corin antibody is conjugated to Biotin

Application: ELISA

Cross-Reactivity: Human, Rat, Sheep

Predicted Reactivity: Mouse,Dog,Pig,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Corin

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for Corin

Target: Corin (CORIN) (Corin, Serine Peptidase (CORIN))

Alternative Name: Corin (CORIN Products)

Synonyms: CORIN antibody, CG2105 antibody, Dmel\\CG2105 antibody, SP75 antibody, LOC559109 antibody, AV273130 antibody, Lrp4 antibody, ATC2 antibody, CRN antibody, PEE5 antibody, TMPRSS10 antibody, corin, serine peptidase antibody, CG2105 gene product from transcript CG2105-RC antibody, novel protein similar to H.sapiens CORIN, corin, serine peptidase (CORIN) antibody, corin antibody, CORIN antibody, Corin antibody, LOC559109 antibody

Background:

Synonyms: CRN, ATC2, Lrp4, PEE5, TMPRSS10, Atrial natriuretic peptide-converting enzyme, Corin, Heart-specific serine proteinase ATC2, Pro-ANP-converting enzyme, Transmembrane protease serine 10

Background: Serine-type endopeptidase involved in atrial natriuretic peptide hormone (NPPA) processing. Converts through proteolytic cleavage the non-functional propeptide NPPA into the active hormone, thereby regulating blood pressure in heart and promoting natriuresis, diuresis and vasodilation. Proteolytic cleavage of pro-NPPA also plays a role in female pregnancy by promoting trophoblast invasion and spiral artery remodeling in uterus. Also acts as a regulator of sodium reabsorption in kidney. May also process pro-NPPB the B-type natriuretic peptide. Isoform 2: has weaker endopeptidase activity compared to isoform 1.

Gene ID: 10699

UniProt: Q9Y5Q5

Pathways: Regulation of Systemic Arterial Blood Pressure by Hormones