Collagen IV antibody (AA 1571-1669) (AbBy Fluor® 488)
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- Target See all Collagen IV (COL4) Antibodies
- Collagen IV (COL4) (Collagen, Type IV (COL4))
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Binding Specificity
- AA 1571-1669
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Reactivity
- Human, Mouse, Rat, Pig
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Collagen IV antibody is conjugated to AbBy Fluor® 488
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Application
- Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))
- Cross-Reactivity
- Human, Mouse, Pig, Rat
- Predicted Reactivity
- Dog,Cow,Horse,Chicken,Rabbit
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human Collagen alpha-1(IV) chain
- Isotype
- IgG
- Top Product
- Discover our top product COL4 Primary Antibody
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- Application Notes
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FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Expiry Date
- 12 months
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Engineering human cell spheroids to model embryonic tissue fusion in vitro." in: PLoS ONE, Vol. 12, Issue 9, pp. e0184155, (2017) (PubMed).
: "
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Engineering human cell spheroids to model embryonic tissue fusion in vitro." in: PLoS ONE, Vol. 12, Issue 9, pp. e0184155, (2017) (PubMed).
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- Target
- Collagen IV (COL4) (Collagen, Type IV (COL4))
- Alternative Name
- Collagen 4 (COL4 Products)
- Synonyms
- collagen, type IV antibody, Let-2 antibody
- Background
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Synonyms: ICH, HANAC, POREN1, arresten, Collagen alpha-1(IV) chain, COL4A1
Background: Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen. Arresten, comprising the C-terminal NC1 domain, inhibits angiogenesis and tumor formation. The C-terminal half is found to possess the anti-angiogenic activity. Specifically inhibits endothelial cell proliferation, migration and tube formation. Inhibits expression of hypoxia-inducible factor 1alpha and ERK1/2 and p38 MAPK activation. Ligand for alpha1/beta1 integrin.
- Gene ID
- 1282
- UniProt
- P02462
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