ICMT antibody (AA 211-278) (Biotin)

Catalog No. ABIN891463

Product Details anti-ICMT Antibody (Biotin)

Target: ICMT (Isoprenylcysteine Carboxyl Methyltransferase (ICMT))

Binding Specificity: AA 211-278

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ICMT antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Human, Mouse

Predicted Reactivity: Rat,Dog,Cow,Sheep,Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from Human ICMT (C-terminus)

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for ICMT

Target: ICMT (Isoprenylcysteine Carboxyl Methyltransferase (ICMT))

Alternative Name: ICMT (ICMT Products)

Background:

Synonyms: HSTE14, Icmt, ICMT_HUMAN, Isoprenylcysteine carboxylmethyltransferase, pcCMT, PCMT, PPMT, Prenylated protein carboxyl methyltransferase, Prenylcysteine carboxyl methyltransferase, Protein-S-isoprenylcysteine O-methyltransferase

Background: Catalyzes the post-translational methylation of isoprenylated C-terminal cysteine residues.Tissue specificity:Ubiquitously expressed. Expressed at higher levels in the cerebellum and putamen than in other brain regions. Abundant expression seen in the Purkinje cells and pontine neurons.

Gene ID: 23463

UniProt: O60725