CETP antibody (AA 355-450) (AbBy Fluor® 488)

Catalog No. ABIN890259

Product Details anti-CETP Antibody (AbBy Fluor® 488)

Target: CETP (Cholesteryl Ester Transfer Protein (CETP))

Binding Specificity: AA 355-450

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CETP antibody is conjugated to AbBy Fluor® 488

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity: Mouse

Predicted Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CETP

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for CETP

Target: CETP (Cholesteryl Ester Transfer Protein (CETP))

Alternative Name: CETP (CETP Products)

Synonyms: BPIFF antibody, HDLCQ10 antibody, hdlcq10 antibody, cholesteryl ester transfer protein antibody, cholesteryl ester transfer protein L homeolog antibody, CETP antibody, cetp.L antibody, Cetp antibody

Background:

Synonyms: BPF, CETP, CETP_HUMAN, Cholesteryl ester transfer, Cholesteryl ester transfer protein, Cholesteryl ester transfer protein plasma, Cholesteryl ester transfer protein precursor, HDLCQ10, Lipid transfer protein I.

Background: High density lipoproteins (HDLs) have been proposed to function jointly with lecithin:cholesterol acyltransferase and CETP to facilitate cholesterol transport from tissues to the liver. This mechanism, referred to as reverse cholesterol transport, is physiologically important because it maintains systemic cholesterol levels. CETP is responsible for neutral lipid transfer activity in plasma in numerous species. Since CETP is able to accelerate specifically the exchange of lipid components between pro- and anti-atherogenic lipoprotein fractions, it may be a key determinant of the global atherogenicity of the plasma lipoprotein profile and arises as a possible target in atherosclerosis prevention. CETP has an important role in reverse cholesterol transport and shaping and affecting the composition of plasma lipoproteins. In general elevated levels of CETP have been associated with increased risk of coronary heart disease.

Gene ID: 1071