CDCA5 antibody (AA 101-200) (HRP)

Catalog No. ABIN889683

Product Details anti-CDCA5 Antibody (HRP)

Target: CDCA5 (Cell Division Cycle Associated 5 (CDCA5))

Binding Specificity: AA 101-200

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDCA5 antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Human, Mouse

Predicted Reactivity: Rat,Dog,Cow,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Sororin

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for CDCA5

Target: CDCA5 (Cell Division Cycle Associated 5 (CDCA5))

Alternative Name: Sororin (CDCA5 Products)

Synonyms: SORORIN antibody, 2610036L13Rik antibody, AL024086 antibody, AW536684 antibody, C85404 antibody, CDCA5 antibody, RGD1560863 antibody, sororin antibody, cdca5 antibody, cell division cycle associated 5 antibody, cell division cycle associated 5 S homeolog antibody, CDCA5 antibody, Cdca5 antibody, cdca5 antibody, cdca5.S antibody

Background:

Synonyms: SORORIN, Cell division cycle-associated protein 5, p35, CDCA5

Background: Regulator of sister chromatid cohesion in mitosis stabilizing cohesin complex association with chromatin. May antagonize the action of WAPAL which stimulates cohesin dissociation from chromatin. Cohesion ensures that chromosome partitioning is accurate in both meiotic and mitotic cells and plays an important role in DNA repair. Required for efficient DNA double-stranded break repair.

Gene ID: 113130

UniProt: Q96FF9

Pathways: Chromatin Binding