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CDC14B antibody (AA 65-160) (Cy5)

CDC14B Reactivity: Human, Mouse, Rat IF (cc), IF (p) Host: Rabbit Polyclonal Cy5
Catalog No. ABIN889447
  • Target See all CDC14B Antibodies
    CDC14B (CDC14 Cell Division Cycle 14B (CDC14B))
    Binding Specificity
    • 14
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 65-160
    Reactivity
    Human, Mouse, Rat
    Host
    • 26
    • 4
    Rabbit
    Clonality
    • 30
    Polyclonal
    Conjugate
    • 11
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CDC14B antibody is conjugated to Cy5
    Application
    • 12
    • 12
    • 10
    • 6
    • 3
    • 3
    • 3
    • 2
    • 1
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Cross-Reactivity
    Human, Mouse, Rat
    Predicted Reactivity
    Rabbit
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human CDC14B
    Isotype
    IgG
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    Discover our top product CDC14B Primary Antibody
  • Application Notes
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    CDC14B (CDC14 Cell Division Cycle 14B (CDC14B))
    Alternative Name
    CDC14B (CDC14B Products)
    Synonyms
    CDC14B antibody, 2810432N10Rik antibody, A530086E13Rik antibody, AA472821 antibody, CDC14B3 antibody, Cdc14B1 antibody, Cdc14B2 antibody, hCDC14B antibody, Dual specificity protein phosphatase CDC14B antibody, dual specificity protein phosphatase CDC14B antibody, cell division cycle 14B antibody, CDC14 cell division cycle 14B antibody, Bm1_19115 antibody, LOAG_10083 antibody, CDC14B antibody, cdc14b antibody, Cdc14b antibody
    Background

    Synonyms: CDC14B3, Cdc14B1, Cdc14B2, hCDC14B, Dual specificity protein phosphatase CDC14B, CDC14 cell division cycle 14 homolog B, CDC14B

    Background: Dual-specificity phosphatase involved in DNA damage response. Essential regulator of the G2 DNA damage checkpoint: following DNA damage, translocates to the nucleus and dephosphorylates FZR1/CDH1, a key activator of the anaphase promoting complex/cyclosome (APC/C). Dephosphorylates SIRT2 around early anaphase. Dephosphorylation of FZR1/CDH1 activates the APC/C, leading to the ubiquitination of PLK1, preventing entry into mitosis. Preferentially dephosphorylates proteins modified by proline-directed kinases.

    Gene ID
    8555
    UniProt
    O60729
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