CDC14B antibody (AA 65-160) (Cy5)
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- Target See all CDC14B Antibodies
- CDC14B (CDC14 Cell Division Cycle 14B (CDC14B))
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Binding Specificity
- AA 65-160
- Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This CDC14B antibody is conjugated to Cy5
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Application
- Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Cross-Reactivity
- Human, Mouse, Rat
- Predicted Reactivity
- Rabbit
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human CDC14B
- Isotype
- IgG
- Top Product
- Discover our top product CDC14B Primary Antibody
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anti-CDC14 Cell Division Cycle 14B (CDC14B) (AA 360-459) antibody
CDC14B Reactivity: Human WB, ELISA Host: Mouse Polyclonal unconjugated
anti-CDC14 Cell Division Cycle 14B (CDC14B) (AA 1-471) antibodyCDC14B Reactivity: Human WB, IP Host: Rabbit Polyclonal unconjugated
anti-CDC14 Cell Division Cycle 14B (CDC14B) (AA 188-215) antibodyCDC14B Reactivity: Human WB, FACS Host: Rabbit Polyclonal RB16909 unconjugated
anti-CDC14 Cell Division Cycle 14B (CDC14B) (AA 1-471) antibodyCDC14B Reactivity: Human WB, IF Host: Mouse Polyclonal unconjugated
anti-CDC14 Cell Division Cycle 14B (CDC14B) (AA 65-160) antibodyCDC14B Reactivity: Human, Mouse, Rat IF (cc), IF (p), ELISA, IHC (fro), IHC (p) Host: Rabbit Polyclonal unconjugated
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- Application Notes
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- CDC14B (CDC14 Cell Division Cycle 14B (CDC14B))
- Alternative Name
- CDC14B (CDC14B Products)
- Background
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Synonyms: CDC14B3, Cdc14B1, Cdc14B2, hCDC14B, Dual specificity protein phosphatase CDC14B, CDC14 cell division cycle 14 homolog B, CDC14B
Background: Dual-specificity phosphatase involved in DNA damage response. Essential regulator of the G2 DNA damage checkpoint: following DNA damage, translocates to the nucleus and dephosphorylates FZR1/CDH1, a key activator of the anaphase promoting complex/cyclosome (APC/C). Dephosphorylates SIRT2 around early anaphase. Dephosphorylation of FZR1/CDH1 activates the APC/C, leading to the ubiquitination of PLK1, preventing entry into mitosis. Preferentially dephosphorylates proteins modified by proline-directed kinases.
- Gene ID
- 8555
- UniProt
- O60729
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