CCDC42 antibody (AA 221-312) (AbBy Fluor® 350)

Catalog No. ABIN887727

Product Details anti-CCDC42 Antibody (AbBy Fluor® 350)

Target: CCDC42 (Coiled-Coil Domain Containing 42 (CCDC42))

Binding Specificity: AA 221-312

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCDC42 antibody is conjugated to AbBy Fluor® 350

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))

Cross-Reactivity: Mouse, Rat

Predicted Reactivity: Human,Dog,Cow,Sheep,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CCDC42

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for CCDC42

Target: CCDC42 (Coiled-Coil Domain Containing 42 (CCDC42))

Alternative Name: CCDC42 (CCDC42 Products)

Synonyms: RGD1565925 antibody, CCDC42A antibody, A530001H01Rik antibody, coiled-coil domain containing 42 antibody, Ccdc42 antibody, CCDC42 antibody

Background:

Synonyms: CCDC42A, Coiled coil domain containing 42, Coiled coil domain containing protein 42A, FLJ32734, OTTMUSP00000006142, RGD1565925, RP23-400O5.1, CCD42_HUMAN.

Background: The coiled-coil domain is a structural motif found in proteins that are involved in a diverse array of biological functions such as the regulation of gene expression, cell division, membrane fusion and drug extrusion and delivery. CCDC42 (coiled-coil domain containing 42) is a 316 amino acid protein encoded by a gene that maps to human chromosome 17p13.1. Encoding over 1,200 genes, chromosome 17 comprises over 2.5 % of the human genome. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Tumor suppressor p53 is necessary for maintenance of cellular genetic integrity by moderating cell fate through DNA repair versus cell death. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome.

Gene ID: 146849