CAPN12 antibody (AA 201-310) (HRP)

Catalog No. ABIN886181

Product Details anti-CAPN12 Antibody (HRP)

Target: CAPN12 (Calpain 12 (CAPN12))

Binding Specificity: AA 201-310

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CAPN12 antibody is conjugated to HRP

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Calpain 12

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for CAPN12

Target: CAPN12 (Calpain 12 (CAPN12))

Alternative Name: Calpain 12 (CAPN12 Products)

Synonyms: CANP 12 antibody, calpain 12 antibody, calpain-12 antibody, CAPN12 antibody, LOC484525 antibody, Capn12 antibody

Background:

Synonyms: Calpain12, Calpain-12, CAPN 12, CAPN12, EC 3.4.22., MGC20576, CAN12_HUMAN.

Background: Calpains are a family of cytosolic calcium activated cysteine proteases involved in a variety of cellular processes including apoptosis, cell division, modulation of integrin and cytoskeletal interactions, and synaptic plasticity. Calpain 12 was first described in the mouse, most strongly in the skin, and maps to mouse chromosome 7. Isoforms differ in the carboxyterminal ends, ending with aberrant domain III and lacking domain IV. Domains in the large subunit include the amino terminal domain I, the proteinase domain II, domain III, and the EF hand domain IV, making Calpain 12 most similar to calpains 1 and 2.

Gene ID: 147968