BCLAF1 antibody (AA 301-400) (Biotin)

Catalog No. ABIN885710

Product Details anti-BCLAF1 Antibody (Biotin)

Target: BCLAF1 (BCL2-Associated Transcription Factor 1 (BCLAF1))

Binding Specificity: AA 301-400

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BCLAF1 antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Sheep,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human BCLAF1

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for BCLAF1

Target: BCLAF1 (BCL2-Associated Transcription Factor 1 (BCLAF1))

Alternative Name: BCLAF1 (BCLAF1 Products)

Synonyms: Aa2-041 antibody, Fam54a antibody, Mtfr2 antibody, 2610102K23Rik antibody, 2700025J07Rik antibody, 2810454G14Rik antibody, 5730534O06Rik antibody, AI450190 antibody, AW556225 antibody, Btf antibody, mKIAA0164 antibody, btf antibody, bk211l9.1 antibody, BCLAF1 antibody, DKFZp468F0113 antibody, BTF antibody, bK211L9.1 antibody, BCL2-associated transcription factor 1 antibody, BCL2 associated transcription factor 1 antibody, mitochondrial fission regulator 2 antibody, Bclaf1 antibody, BCLAF1 antibody, bclaf1 antibody, MTFR2 antibody

Background:

Synonyms: Bcl 2 associated transcription factor, Bcl-2-associated transcription factor 1, BCL2 associated transcription factor 1, BCLAF1, BCLF1_HUMAN, Btf.

Background: This gene encodes a transcriptional repressor that interacts with several members of the BCL2 family of proteins. Overexpression of this protein induces apoptosis, which can be suppressed by co-expression of BCL2 proteins. The protein localizes to dot-like structures throughout the nucleus, and redistributes to a zone near the nuclear envelope in cells undergoing apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene ID: 9774

Pathways: Positive Regulation of Response to DNA Damage Stimulus