ASB3 antibody (AA 21-120) (Biotin)
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- Target See all ASB3 Antibodies
- ASB3 (Ankyrin Repeat and SOCS Box-Containing 3 (ASB3))
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Binding Specificity
- AA 21-120
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Reactivity
- Human, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This ASB3 antibody is conjugated to Biotin
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Application
- ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Cross-Reactivity
- Human, Mouse
- Predicted Reactivity
- Rat,Dog,Cow,Rabbit
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human ASB3
- Isotype
- IgG
- Top Product
- Discover our top product ASB3 Primary Antibody
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- Application Notes
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IHC-P 1:200-400
IHC-F 1:100-500 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C for 12 months.
- Expiry Date
- 12 months
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- Target
- ASB3 (Ankyrin Repeat and SOCS Box-Containing 3 (ASB3))
- Alternative Name
- ASB3 (ASB3 Products)
- Synonyms
- ASB-3 antibody, 2400011J03Rik antibody, Asb-3 antibody, fi36b12 antibody, zgc:56163 antibody, wu:fi36b12 antibody, ASB3 antibody, DKFZp459D0910 antibody, asb-3 antibody, asb3 antibody, ankyrin repeat and SOCS box containing 3 antibody, ankyrin repeat and SOCS box-containing 3 antibody, ankyrin repeat and SOCS box containing 3 S homeolog antibody, ASB3 antibody, Asb3 antibody, asb3 antibody, asb3.S antibody
- Background
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Synonyms: Ankyrin repeat and SOCS box containing 3, Ankyrin repeat and SOCS box containing protein 3, Ankyrin repeat and SOCS box protein 3, ASB-3, ASB3, ASB3_HUMAN, Weakly similar to ankyrin brain variant 2.
Background: Members of the suppressor of cytokine signaling (SOCS) family of proteins contain C-terminal regions of homology called the SOCS box, which serves to couple SOCS proteins and their binding partners with the elongin B and C complex. Serveral other families of proteins also contain SOCS boxes but differ from the SOCS proteins in the type of domain they contained upstream of the SOCS box. Four members of the ankyrin repeat and SOCS box-containing (ASB) protein family are identified and termed as ASB-1, ASB-2, ASB-3 and ASB-4. ASB-1 is expressed in multiple organs, including the hematopoietic compartment. ASB-1 knock-out mice display a diminution of spermatogenesis with less complete filling of seminiferous tubules. Asb-2 is a novel retinoic-acid (RA)-induced gene in acute promyelocytic leukemia (APL) cells and its expression induces growth-inhibition and chromatin condensation recapitulating early events critical to RA-induced differentiaiton of APL cells. ASB-2 is directly induced by all-trans retinotic acid, by the binding of RARa to the RAR binding element/RXR binding element in the Asb-2 promoter.
- Gene ID
- 51130
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