Apoptosis Inhibitor 5 antibody (AA 351-460) (AbBy Fluor® 488)

Catalog No. ABIN883022

Product Details anti-Apoptosis Inhibitor 5 Antibody (AbBy Fluor® 488)

Target: Apoptosis Inhibitor 5 (API5)

Binding Specificity: AA 351-460

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Apoptosis Inhibitor 5 antibody is conjugated to AbBy Fluor® 488

Application: Western Blotting (WB), Flow Cytometry (FACS)

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Dog,Cow,Pig,Horse,Guinea Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human API5

Isotype: IgG

Application Details

Application Notes: FCM 1:20-100

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for Apoptosis Inhibitor 5

Target: Apoptosis Inhibitor 5 (API5)

Alternative Name: API5 (API5 Products)

Synonyms: AAC-11 antibody, AAC11 antibody, AI196452 antibody, api5l1 antibody, sr:nyz021 antibody, zgc:66211 antibody, wu:fb26c03 antibody, API-5B antibody, aac-11 antibody, aac11 antibody, api5 antibody, API-5A antibody, api5-A antibody, MGC83290 antibody, API5 antibody, apoptosis inhibitor 5 antibody, apoptosis inhibitor 5 S homeolog antibody, apoptosis inhibitor 5 L homeolog antibody, API5 antibody, Api5 antibody, api5 antibody, api5.S antibody, api5.L antibody

Background:

Synonyms: AAC11, AAC-11, Apoptosis inhibitor 5, API-5, Antiapoptosis clone 11 protein, Cell migration-inducing gene 8 protein, Fibroblast growth factor 2-interacting factor, FIF, Protein XAGL, API5, MIG8

Background: Antiapoptotic factor that may have a role in protein assembly. Negatively regulates ACIN1. By binding to ACIN1, it suppresses ACIN1 cleavage from CASP3 and ACIN1-mediated DNA fragmentation. Also known to efficiently suppress E2F1-induced apoptosis. Its depletion enhances the cytotoxic action of the chemotherapeutic drugs.

Gene ID: 8539

UniProt: Q9BZZ5

Pathways: Growth Factor Binding