MLLT10 antibody (AA 151-250) (AbBy Fluor® 350)

Catalog No. ABIN881749

Product Details anti-MLLT10 Antibody (AbBy Fluor® 350)

Target: MLLT10 (Protein AF-10 (MLLT10))

Binding Specificity: AA 151-250

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MLLT10 antibody is conjugated to AbBy Fluor® 350

Application: Western Blotting (WB), Flow Cytometry (FACS)

Cross-Reactivity: Human, Rat

Predicted Reactivity: Mouse,Dog,Cow,Sheep,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human AF10/MLLT10

Isotype: IgG

Application Details

Application Notes: FCM 1:20-100

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for MLLT10

Target: MLLT10 (Protein AF-10 (MLLT10))

Alternative Name: AF10 (MLLT10 Products)

Synonyms: AF10 antibody, Af10 antibody, B130021D15Rik antibody, D630001B22Rik antibody, mKIAA4140 antibody, MLLT10, histone lysine methyltransferase DOT1L cofactor antibody, myeloid/lymphoid or mixed-lineage leukemia; translocated to, 10 antibody, MLLT10 antibody, Mllt10 antibody

Background:

Synonyms: AF 10, AF10, AF10_HUMAN, ALL 1 fused gene from chromosome 10, ALL1 fused gene from chromosome 10, ALL1-fused gene from chromosome 10 protein, MLLT 10, MLLT10, Myeloid/lymphoid or mixed lineage leukemia trithorax homolog Drosophila translocated to 10, Myeloid/lymphoid or mixed lineage leukemia translocated to 10, Protein AF 10, Protein AF-10, Protein AF10, Type I AF10 protein.

Background: A chromosomal aberration involving MLLT10 is associated with acute leukemias. Translocation t(10,11)(p12,q23) with MLL/HRX. The result is a rogue activator protein.A chromosomal aberration involving MLLT10 is associated with diffuse histiocytic lymphomas. Translocation t(10,11)(p13,q14) with PICALM.

Gene ID: 8028