Adenylosuccinate Lyase antibody (AA 185-280) (AbBy Fluor® 488)
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- Target See all Adenylosuccinate Lyase (ADSL) Antibodies
- Adenylosuccinate Lyase (ADSL)
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Binding Specificity
- AA 185-280
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Reactivity
- Human, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Adenylosuccinate Lyase antibody is conjugated to AbBy Fluor® 488
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Application
- Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))
- Cross-Reactivity
- Human, Mouse
- Predicted Reactivity
- Rat,Dog,Cow,Pig,Horse
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human Adenylosuccinate Lyase
- Isotype
- IgG
- Top Product
- Discover our top product ADSL Primary Antibody
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- Application Notes
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- Adenylosuccinate Lyase (ADSL)
- Alternative Name
- Adenylosuccinate Lyase (ADSL Products)
- Synonyms
- fi60b04 antibody, zgc:56061 antibody, wu:fi60b04 antibody, MGC53383 antibody, MGC69239 antibody, adsL antibody, F15C21.8 antibody, F15C21_8 antibody, AMPS antibody, ASASE antibody, ASL antibody, Adl antibody, Asl antibody, purB antibody, adenylosuccinate lyase antibody, adenylosuccinate lyase L homeolog antibody, adenylosuccinase; ASL antibody, Adenylosuccinate lyase antibody, L-Aspartase-like family protein antibody, ADSL antibody, adsl antibody, adsl.L antibody, ASL antibody, purB antibody, purB,adsL antibody, Mrub_2293 antibody, MMAH_RS02975 antibody, Arnit_0089 antibody, Mesil_1058 antibody, Slip_0597 antibody, Trad_2452 antibody, Deba_0652 antibody, Toce_1174 antibody, Acear_2324 antibody, Igag_0272 antibody, Saut_2156 antibody, Fbal_1996 antibody, Ndas_2434 antibody, Ilyop_0196 antibody, Lbys_2961 antibody, MFER_RS02920 antibody, Palpr_2192 antibody, Calni_0061 antibody, Ftrac_3746 antibody, AT1G36280 antibody, Olsu_1764 antibody, Adsl antibody
- Background
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Synonyms: Adenylosuccinase, Adenylosuccinate lyase, ADSL, AMPS, ASase, ASL, PUR8_HUMAN.
Background: Adenylsuccinate lyase is involved in both de novo synthesis of purines and formation of adenosine monophosphate from inosine monophosphate. It catalyzes two reactions in AMP biosynthesis: the removal of a fumarate from succinylaminoimidazole carboxamide (SAICA) ribotide to give aminoimidazole carboxamide ribotide (AICA) and removal of fumarate from adenylosuccinate to give AMP. Adenylosuccinase deficiency results in succinylpurinemic autism, psychomotor retardation, and , in some cases, growth retardation associated with muscle wasting and epilepsy. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
- Pathways
- Ribonucleoside Biosynthetic Process
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