INPPL1 antibody (pTyr986, pTyr987) (AbBy Fluor® 350)
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- Target See all INPPL1 Antibodies
- INPPL1 (Inositol Polyphosphate Phosphatase-Like 1 (INPPL1))
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Binding Specificity
- pTyr986, pTyr987
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This INPPL1 antibody is conjugated to AbBy Fluor® 350
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Application
- Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Predicted Reactivity
- Human,Mouse,Rat,Dog,Cow,Pig,Horse,Rabbit
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic phosphopeptide derived from human SHIP2 around the phosphorylation site of Tyr986/987
- Isotype
- IgG
- Top Product
- Discover our top product INPPL1 Primary Antibody
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- Application Notes
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- INPPL1 (Inositol Polyphosphate Phosphatase-Like 1 (INPPL1))
- Alternative Name
- INPPL1 + (INPPL1 Products)
- Synonyms
- OPSMD antibody, SHIP2 antibody, 51C antibody, Ship2 antibody, inppl1 antibody, si:bz46j2.7 antibody, si:rp71-46j2.7 antibody, INPPL1 antibody, fc58a04 antibody, wu:fc58a04 antibody, zgc:198309 antibody, inositol polyphosphate phosphatase like 1 antibody, inositol polyphosphate phosphatase-like 1 antibody, inositol polyphosphate phosphatase-like 1b antibody, phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2B antibody, inositol polyphosphate phosphatase-like 1a antibody, INPPL1 antibody, Inppl1 antibody, inppl1b antibody, LOC100180571 antibody, inppl1a antibody
- Background
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Synonyms: 4, 5-trisphosphate 5-phosphatase 2, 51C protein, EC 3.1.3.n1, inositol polyphosphate phosphatase like 1, Inositol polyphosphate phosphatase like protein 1, Inositol polyphosphate phosphatase-like protein 1, INPPL-1, INPPL1, Phosphatidylinositol 3, Phosphatidylinositol 3,4,5 trisphosphate 5 phosphatase 2, Protein 51C, SH2 domain containing inositol 5' phosphatase 2, SH2 domain-containing inositol 5''-phosphatase 2, SH2 domain-containing inositol phosphatase 2, SHIP-2, SHIP2, SHIP2_HUMAN.
Background: The steady state of protein tyrosyl phosphorylation in cells is regulated by the opposing action of tyrosine kinases and protein tyrosine phosphatases (PTPs). Several groups have independently identified a non transmembrane PTP, designated SHPTP1 (also known as PTP1C, HCP and SHP), which is primarily expressed in hematopoietic cells and characterized by the presence of two SH2 domains N terminal to the PTP domain. A second and much more widely expressed PTP with SH2 domains, SHPTP2 (also designated PTP1D and Syp), has been identified. SHP2 is a protein tyrosine phosphatase that is widely expressed and plays a regulatory role in various cell signaling events that are important for many cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration.
- Gene ID
- 3636
- Pathways
- Platelet-derived growth Factor Receptor Signaling
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