DLG2 antibody (pTyr340) (AbBy Fluor® 488)

Catalog No. ABIN879522

Product Details anti-DLG2 Antibody (AbBy Fluor® 488)

Target: DLG2 (Discs, Large Homolog 2 (DLG2))

Binding Specificity: pTyr340

Reactivity: Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DLG2 antibody is conjugated to AbBy Fluor® 488

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity: Mouse, Rat

Predicted Reactivity: Human,Dog,Horse,Chicken

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human PSD93 around the phosphorylation site of Tyr340

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for DLG2

Target: DLG2 (Discs, Large Homolog 2 (DLG2))

Alternative Name: PSD93 (DLG2 Products)

Synonyms: PPP1R58 antibody, PSD-93 antibody, PSD93 antibody, chapsyn-110 antibody, A330103J02Rik antibody, B230218P12Rik antibody, B330007M19Rik antibody, Dlgh2 antibody, Gm1197 antibody, discs, large homolog 2 (Drosophila) antibody, discs large MAGUK scaffold protein 2 antibody, dlg2 antibody, DLG2 antibody, Dlg2 antibody

Background:

Synonyms: Channel associated protein of synapse 110, Channel associated protein of synapses 110kD, Channel-associated protein of synapse-110, Chapsyn 110, Chapsyn-110, Chapsyn110, discs large homolog 2, Discs, large homolog 2 Drosophila, Disks large homolog 2, DKFZp781D1854, DKFZp781E0954, Dlg 2, dlg2, DLG2_HUMAN, Dlgh 2, Dlgh2, FLJ37266, Gm1197, MGC131811, Postsynaptic density protein PSD 93, Postsynaptic density protein PSD-93, Postsynaptic density protein PSD93, PSD 93, PSD93.

Background: PSD 93 is believed to participate in the clustering of certain proteins, including N-methyl-D-aspartate (NMDA) receptors and shaker-type potassium channels at the synaptic membrane. There are two principal modes of interaction between PSD 93 and other proteins. NMDA receptors and shaker-type potassium channels both share C-terminal sequence homology consisting of a threonine/serine-X-valine-COOH (T/SXV) motif. Other neuronal proteins that share this motif (beta 1 adrenergic receptor, some serotonin receptors, some sodium channel subunits, and additional potassium channel subunits) may interact with PSD 93 by binding to its PDZ domains. Neuronal nitric oxide synthase (nNOS), which lacks the T/SXV motif but which has its own PDZ domain, has been shown to associate with PSD 93 in vitro through a pseudo-homotypic PDZ-PDZ interaction.

Gene ID: 1740