GPRIN2 antibody (AA 251-350)

Catalog No. ABIN873317

Product Details anti-GPRIN2 Antibody

Target: GPRIN2 (G Protein Regulated Inducer of Neurite Outgrowth 2 (GPRIN2))

Binding Specificity: AA 251-350

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GPRIN2 antibody is un-conjugated

Application: ELISA, Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Predicted Reactivity: Human,Mouse,Rat,Dog,Pig,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GPRIN2

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for GPRIN2

Target: GPRIN2 (G Protein Regulated Inducer of Neurite Outgrowth 2 (GPRIN2))

Alternative Name: Gprin2 (GPRIN2 Products)

Synonyms: GRIN2 antibody, KIAA0514 antibody, C130040D06Rik antibody, C230073P13 antibody, Gm286 antibody, mKIAA0514 antibody, RGD1308922 antibody, IP6 antibody, G protein regulated inducer of neurite outgrowth 2 antibody, GPRIN2 antibody, Gprin2 antibody

Background:

Synonyms: G protein-regulated inducer of neurite outgrowth 2, Gm286, G protein-regulated inducer of neurite outgrowth 2, GPRIN2, GRIN2, GRIN2_HUMAN, MGC15171, mKIAA0514, RGD1308922.

Background: G protein-coupled receptors (GPCRs) represent a large superfamily of cell-surface receptors that are involved in a multitude of physiological processes such as perception of sensory information, modulation of synaptic transmission, hormone release/actions, regulation of cell contraction/migration and cell growth/differentiation. GPCRs interact with G proteins (heterotrimeric GTPases) to synthesize intracellular second messengers, such as diacylglycerol, cyclic AMP, inositol phosphates and calcium ions. Their diverse biological functions range from vision and olfaction to neuronal and endocrine signaling and are involved in many pathological conditions. GRIN2 (G protein-regulated inducer of neurite outgrowth 2), also known as GPRIN2, is a 458 amino acid protein that is expressed in cerebellum and is thought to play a role in neurite outgrowth. GRIN2 interacts with activated G?oand G?, and is encoded by a gene that maps to human chromosome 10q11.22.

Gene ID: 9721