PCNT antibody (AA 3101-3200)

Catalog No. ABIN873305

Product Details anti-PCNT Antibody

Target: PCNT (Pericentrin (PCNT))

Binding Specificity: AA 3101-3200

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PCNT antibody is un-conjugated

Application: ELISA, Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Dog,Cow,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Pericentrin

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for PCNT

Target: PCNT (Pericentrin (PCNT))

Alternative Name: PCNT (PCNT Products)

Background:

Synonyms: Centrosome Marker, Ken, Kendrin, KIAA0402, MOPD2, PCN, PCNT 2, PCNT, PCNT B, PCNT1, PCNT2, PCNTB, PCTN2, Pericentrin 1, Pericentrin 1, Pericentrin 2, Pericentrin 380, Pericentrin B, SCKL4.

Background: The protein encoded by this gene binds to calmodulin and is expressed in the centrosome. It is an integral component of the pericentriolar material (PCM). The protein contains a series of coiled-coil domains and a highly conserved PCM targeting motif called the PACT domain near its C-terminus. The protein interacts with the microtubule nucleation component gamma-tubulin and is likely important to normal functioning of the centrosomes, cytoskeleton, and cell-cycle progression. Mutations in this gene cause Seckel syndrome-4 and microcephalic osteodysplastic primordial dwarfism type II. [provided by RefSeq, Jul 2008].

Gene ID: 5116

Pathways: Sensory Perception of Sound, M Phase, SARS-CoV-2 Protein Interactome