CCAR1 antibody (AA 731-830)

Catalog No. ABIN873295

Product Details anti-CCAR1 Antibody

Target: CCAR1 (Cell Division Cycle and Apoptosis Regulator 1 (CCAR1))

Binding Specificity: AA 731-830

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCAR1 antibody is un-conjugated

Application: ELISA, Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Sheep,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human DIS/CCAR1

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for CCAR1

Target: CCAR1 (Cell Division Cycle and Apoptosis Regulator 1 (CCAR1))

Alternative Name: CCAR1 (CCAR1 Products)

Synonyms: CCAR1 antibody, KIAA1967 antibody, ccar1 antibody, MGC81663 antibody, zehn1480 antibody, hm:zehn1480 antibody, si:dkey-85g17.2 antibody, RP11-437A18.1 antibody, CARP-1 antibody, 2610511G16Rik antibody, 9430036H15Rik antibody, Carp1 antibody, RGD1560358 antibody, cell division cycle and apoptosis regulator 1 antibody, cell division cycle and apoptosis regulator 1 L homeolog antibody, cell division cycle and apoptosis regulator protein 1 antibody, CCAR1 antibody, ccar1.L antibody, LOC5575286 antibody, ccar1 antibody, LOC409891 antibody, Ccar1 antibody

Background:

Synonyms: CARP-1, Carp1, CCAR1, CCAR1_HUMAN, Cell cycle and apoptosis regulatory protein 1, cell division cycle and apoptosis regulator 1, Cell division cycle and apoptosis regulator protein 1, Death Inducer with SAP domain, FLJ10590, FLJ10839, FLJ13376, FLJ20734, MGC7730, RP11-437A18.1.

Background: Associates with components of the Mediator and p160 coactivator complexes that play a role as intermediaries transducing regulatory signals from upstream transcriptional activator proteins to basal transcription machinery at the core promoter. Recruited to endogenous nuclear receptor target genes in response to the appropriate hormone. Also functions as a p53 coactivator. May thus play an important role in transcriptional regulation (By similarity). May be involved in apoptosis signaling in the presence of the reinoid CD437. Apoptosis induction involves sequestration of 14-3-3 protein(s) and mediated altered expression of multiple cell cycle regulatory genes including MYC, CCNB1 and CDKN1A. Plays a role in cell cycle progression and/or cell proliferation.

Gene ID: 55749