SRPK2 antibody (AA 266-350)

Catalog No. ABIN873168

Product Details anti-SRPK2 Antibody

Target: SRPK2 (SFRS Protein Kinase 2 (SRPK2))

Binding Specificity: AA 266-350

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SRPK2 antibody is un-conjugated

Application: ELISA, Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Human, Mouse

Predicted Reactivity: Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SRPK2

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for SRPK2

Target: SRPK2 (SFRS Protein Kinase 2 (SRPK2))

Alternative Name: SRPK2 (SRPK2 Products)

Synonyms: SFRSK2 antibody, AW226533 antibody, AW492537 antibody, AW547358 antibody, Wbp6 antibody, mSRPK2 antibody, sfrsk2 antibody, srpk2 antibody, srpk2-b antibody, srpk2b antibody, SRSF protein kinase 2 antibody, serine/arginine-rich protein specific kinase 2 antibody, SRSF protein kinase 2 L homeolog antibody, SRPK2 antibody, Srpk2 antibody, srpk2 antibody, srpk2.L antibody

Background:

Synonyms: Human serine kinase SRPK2 mRNA, complete cds, Serine kinase SRPK2, Serine/arginine rich protein specic kinase 2, Serine/threonine protein kinase SRPK2, SFRS protein kinase 2, SFRSK2, SR protein specic kinase 2, SRPK2_HUMAN.

Background: SRPK2 belongs to the protein kinase superfamily. It phosphorylates RS domain-containing proteins, such as SFRS1 and SFRS2 on serine residues. It has a role in spliceosome assembly and in mediating the trafficking of splicing factors and appears to mediate HBV core protein phosphorylation which is a prerequisite for pregenomic RNA encapsidation into viral capsids. SRPK2 highly expressed in brain, moderately expressed in heart and skeletal muscle and at low levels in lung, liver, and kidney.

Gene ID: 6733

Pathways: Ribonucleoprotein Complex Subunit Organization