KIFC1 antibody

Catalog No. ABIN873143

Product Details anti-KIFC1 Antibody

Target: KIFC1 (Kinesin Family Member C1 (KIFC1))

Reactivity: Human, Mouse, Rat, Cow, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KIFC1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity: Rat (Rattus), Pig (Porcine), Cow (Bovine)

Purification: purified by Protein A and peptide affinity chromatography

Immunogen: KLH conjugated synthetic peptide derived from human KIFC1

Isotype: IgG

Application Details

Application Notes: WB (1:100-500),IHC-P (1:100-500),IF (p) (1:100-500)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 µg/µL

Buffer: Aqueous buffered solution containing 100 µg/mL BSA, 50 % glycerol and 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C for 12 months

Expiry Date: 12 months

Target Details for KIFC1

Target: KIFC1 (Kinesin Family Member C1 (KIFC1))

Alternative Name: KIFC1 (KIFC1 Products)

Synonyms: HSET antibody, KNSL2 antibody, fc27e02 antibody, fd14g02 antibody, knsl2 antibody, wu:fc27e02 antibody, wu:fd14g02 antibody, hset antibody, ctk2-A antibody, KIFC1 antibody, Xctk2 antibody, mklp2 antibody, rab6-kifl antibody, 100042970 antibody, Gm4137 antibody, Kifc5a antibody, Knsl2a antibody, Tctex-7 antibody, Tctex-7A antibody, Tctex7 antibody, Tctex7a antibody, kinesin family member C1 antibody, kinesin family member C1 L homeolog antibody, KIFC1 antibody, kifc1 antibody, Kifc1 antibody, kifc1.L antibody

Background: The kinesins constitute a large family of microtubule-dependent motor proteins, which are responsible for the distribution of numerous organelles, vesicles and macromolecular complexes throughout the cell. Individual kinesin members play crucial roles in cell division, intracellular transport and membrane trafficking events including endocytosis and transcytosis. KIFC1 is a 673 amino acid protein that belongs to the kinesin-like family of proteins. KIFC1 localizes to the nucleus and contains a C-terminal kinesin-motor domain. Functioning as a minus-end directed microtubule-dependent motor, KIFC1 works together with NuMA and cytoplasmic Dynein to organize microtubule minus ends at spindle poles. HeLa cells deficient in KIFC1 exhibit multipolar mitotic spindles, suggesting that KIFC1 is essential for bipolar spindle formation.

Molecular Weight: 74kDa

Gene ID: 3833