FRMD6 antibody (AA 51-150)

Catalog No. ABIN873129

Product Details anti-FRMD6 Antibody

Target: FRMD6 (FERM Domain Containing 6 (FRMD6))

Binding Specificity: AA 51-150

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FRMD6 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Human

Predicted Reactivity: Mouse,Rat,Dog,Cow,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human FRMD6

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for FRMD6

Target: FRMD6 (FERM Domain Containing 6 (FRMD6))

Alternative Name: Frmd6 (FRMD6 Products)

Synonyms: wu:fb38g08 antibody, zgc:110114 antibody, FRMD6 antibody, ex1 antibody, willin antibody, C14orf31 antibody, EX1 antibody, Willin antibody, c14_5320 antibody, 2610019M19Rik antibody, 4930488L10Rik antibody, AW212977 antibody, FERM domain containing 6 antibody, FRMD6 antibody, frmd6 antibody, Frmd6 antibody

Background:

Synonyms: EX1, Willin, C14orf31, c14_5320, FERM domain-containing protein 6, FRMD6

Background: FERM domains are roughly 150 amino acids in length and are found in a number of cytoskeletal-associated proteins such as Ezrin, Radixin, Moesin and 4.1 (erythrocyte membrane protein band 4.1), where they provide a link between cytoskeletal signals and membrane dynamics. FRMD6 (FERM domain containing 6), also known as EX1 or Willin, is a 622 amino acid cytoplasmic and peripheral membrane protein that can colocalize with Actin and exists as three alternatively spliced isoforms. Containing one FERM domain within its N-terminus, FRMD6 binds phospholipids and is encoded by a gene mapping to human chromosome 14, which houses over 700 genes and comprises nearly 3.5 % of the human genome. Chromosome 14 encodes the presinilin 1 (PSEN1) gene, which is one of the three key genes associated with the development of Alzheimer's disease (AD).

Gene ID: 122786

UniProt: Q96NE9