KLHL21 antibody (AA 51-110)

Catalog No. ABIN873084

Product Details anti-KLHL21 Antibody

Target: KLHL21 (Kelch-Like 21 (KLHL21))

Binding Specificity: AA 51-110

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KLHL21 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Sheep,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human KLHL21

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for KLHL21

Target: KLHL21 (Kelch-Like 21 (KLHL21))

Alternative Name: KLHL21 (KLHL21 Products)

Synonyms: zgc:76933 antibody, 1810045K06Rik antibody, D330008A20 antibody, mKIAA0469 antibody, RGD1305863 antibody, kelch-like family member 21 antibody, kelch like family member 21 antibody, kelch like family member 21 L homeolog antibody, kelch-like 21 antibody, klhl21 antibody, KLHL21 antibody, klhl21.L antibody, Klhl21 antibody

Background:

Synonyms: Kelch like protein 21, KIAA0469, KLHL21, MGC99635, KLH21_HUMAN.

Background: Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for efficient chromosome alignment and cytokinesis. The BCR(KLHL21) E3 ubiquitin ligase complex regulates localization of the chromosomal passenger complex (CPC) from chromosomes to the spindle midzone in anaphase and mediates the ubiquitination of AURKB. Ubiquitination of AURKB by BCR(KLHL21) E3 ubiquitin ligase complex may not lead to its degradation by the proteasome.

Gene ID: 9903

Pathways: M Phase