Cyclin L1 antibody (AA 351-450)

Catalog No. ABIN872995

Product Details anti-Cyclin L1 Antibody

Target: Cyclin L1 (CCNL1)

Binding Specificity: AA 351-450

Reactivity: Chimpanzee

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cyclin L1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Chimpanzee

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Chimpanzee

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Cyclin L/CCNL1

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for Cyclin L1

Target: Cyclin L1 (CCNL1)

Alternative Name: Cyclin L (CCNL1 Products)

Background:

Synonyms: Ania 6a, BM 001, CCNL 1, CCNL1, CCNL1_HUMAN, Cyclin L ania 6a, Cyclin L, Cyclin L gamma, Cyclin L1, Cyclin-L, Cyclin-L1.

Background: Transcriptional regulator which participates in regulating the pre-mRNA splicing process. Seems to be involved in the regulation of RNA polymerase II (pol II). Functions in association with cyclin-dependent kinases (CDKs) and has a role in the second step of splicing. May be a candidate proto-oncogene in head and neck squamous cell carcinomas (HNSCC). Inhibited by the CDK-specific inhibitor p21.Tissue specificity,Ubiquitous with higher level in thymus. Overexpression in primary tumors of head and neck squamous cell carcinomas (HNSCC).

Gene ID: 57018