AGFG1 antibody (AA 276-380)

Catalog No. ABIN872992

Product Details anti-AGFG1 Antibody

Target: AGFG1 (HRB) (HIV-1 Rev Binding Protein (HRB))

Binding Specificity: AA 276-380

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AGFG1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human AGFG1

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for AGFG1

Target: AGFG1 (HRB) (HIV-1 Rev Binding Protein (HRB))

Alternative Name: AGFG1 (HRB Products)

Background:

Synonyms: HIV 1 Rev binding protein, RAB, Rev/Rex activation domain-binding protein, RIP, AGFG1, AGFG1_HUMAN, Arf-GAP domain and FG repeats-containing protein 1, ArfGAP with FG repeats 1, HIV-1 Rev-binding protein, HRB, Nucleoporin like protein RIP, Nucleoporin-like protein RIP, Rev interacting protein, Rev-interacting protein.

Background: Required for vesicle docking or fusion during acrosome biogenesis (By similarity). May play a role in RNA trafficking or localization. In case of infection by HIV-1, acts as a cofactor for viral Rev and promotes movement of Rev-responsive element-containing RNAs from the nuclear periphery to the cytoplasm. This step is essential for HIV-1 replication.