TBL1Y antibody (AA 351-450)

Catalog No. ABIN872988

Product Details anti-TBL1Y Antibody

Target: TBL1Y (Transducin (Beta)-Like 1, Y-Linked (TBL1Y))

Binding Specificity: AA 351-450

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TBL1Y antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human TBL1Y

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for TBL1Y

Target: TBL1Y (Transducin (Beta)-Like 1, Y-Linked (TBL1Y))

Alternative Name: Tbl1y (TBL1Y Products)

Synonyms: TBL1 antibody, transducin beta like 1, Y-linked antibody, TBL1Y antibody

Background:

Synonyms: Y-linked, F-box-like/WD repeat-containing protein TBL1Y, TBL1, TBL1Y, TBL1Y_HUMAN, Transducin beta like 1, Y linked, Transducin beta-like 1, Transducin beta-like protein 1Y, Transducin-beta-like protein 1, Transducin-beta-like protein 1, Y-linked.

Background: FunctionF-box-like protein involved in the recruitment of the ubiquitin/19S proteasome complex to nuclear receptor-regulated transcription units. Plays an essential role in transcription activation mediated by nuclear receptors. Probably acts as integral component of corepressor complexes that mediates the recruitment of the 19S proteasome complex, leading to the subsequent proteasomal degradation of transcription repressor complexes, thereby allowing cofactor exchange.

Gene ID: 90665