AEN antibody (AA 1-100)

Catalog No. ABIN872714

Product Details anti-AEN Antibody

Target: AEN (Apoptosis Enhancing Nuclease (AEN))

Binding Specificity: AA 1-100

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AEN antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Sheep,Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Apoptosis enhancing nuclease

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for AEN

Target: AEN (Apoptosis Enhancing Nuclease (AEN))

Alternative Name: Apoptosis enhancing nuclease (AEN Products)

Synonyms: AEN antibody, ISG20L1 antibody, xaen antibody, isg20l1 antibody, MGC147218 antibody, pp12744 antibody, 2700083B06Rik antibody, Isg20l1 antibody, RGD1305051 antibody, apoptosis enhancing nuclease antibody, apoptosis enhancing nuclease L homeolog antibody, AEN antibody, aen.L antibody, aen antibody, Aen antibody

Background:

Synonyms: Aen, AEN_HUMAN, apoptosis enhancing nuclease, Apoptosis-enhancing nuclease, Interferon stimulated exonuclease gene 20 kDa like 1, Interferon stimulated exonuclease gene 20 kDa like 1, isoform CRA_a, Interferon-stimulated 20 kDa exonuclease-like 1, ISG20L1, pp12744.

Background: Exonuclease with activity against single- and double-stranded DNA and RNA. Mediates p53-induced apoptosis. When induced by p53 following DNA damage, digests double-stranded DNA to form single-stranded DNA and amplifies DNA damage signals, leading to enhancement of apoptosis.