DHRS9 antibody (AA 211-319)

Catalog No. ABIN872705

Product Details anti-DHRS9 Antibody

Target: DHRS9 (Dehydrogenase/reductase (SDR Family) Member 9 (DHRS9))

Binding Specificity: AA 211-319

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DHRS9 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Predicted Reactivity: Human,Mouse,Rat,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human DHRS9

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for DHRS9

Target: DHRS9 (Dehydrogenase/reductase (SDR Family) Member 9 (DHRS9))

Alternative Name: DHRS9 (DHRS9 Products)

Background:

Synonyms: Dehydrogenase/reductase SDR family member 9, DHRS9, DHRS9_HUMAN, NADP dependent retinol dehydrogenase/reductase, NADP-dependent retinol dehydrogenase/reductase, RDH-E2, Rdh15, RDHE2, RDHL, RDHTBE, retinol dehydrogenase homolog, Retinol dehydrogenase, tracheobronchiol epithelail cell-specic, RETSDR8, SDR family, member 9, SDR9C4, short chain dehydrogenase/reductase family 9, short chain dehydrogenase/reductase family 9C, member 4, Short chain dehydrogenase/reductase retSDR8, Short-chain dehydrogenase/reductase retSDR8, 3 alpha hydroxysteroid dehydrogenase, 3-alpha hydroxysteroid dehydrogenase, 3-alpha-HSD, 3alpha HSD.

Background: 3-alpha-hydroxysteroid dehydrogenase that converts 3-alpha-tetrahydroprogesterone (allopregnanolone) to dihydroxyprogesterone and 3-alpha-androstanediol to dihydroxyprogesterone. May play a role in the biosynthesis of retinoic acid from retinaldehyde, but seems to have low activity with retinoids. Can utilize both NADH and NADPH.Tissue specificity:Highly expressed in trachea and epidermis. Detected at lower levels in spinal cord, bone marrow, brain, tongue, esophagus, heart, colon, testis, placenta, lung, skeletal muscle and lymph node.

Gene ID: 10170

Pathways: C21-Steroid Hormone Metabolic Process