HIV-1 Tat Interactive Protein 2, 30kDa (HTATIP2) (AA 142-242) antibody

Catalog No. ABIN872606

Product Details

Target: HIV-1 Tat Interactive Protein 2, 30kDa (HTATIP2)

Binding Specificity: AA 142-242

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Predicted Reactivity: Human,Mouse,Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human TIP30

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details

Target: HIV-1 Tat Interactive Protein 2, 30kDa (HTATIP2)

Alternative Name: TIP30 (HTATIP2 Products)

Target Type: Viral Protein

Background:

Synonyms: 30 kDa HIV 1 TAT interacting protein, 30 kDa HIV-1 TAT-interacting protein, 30 kDa HIV1 TAT interacting protein, CC3, HIV 1 Tat interacting protein 2 30 kDa, HIV 1 Tat interacting protein 2, HIV-1 Tat interacting protein 2 30 kDa, HIV-1 TAT-interactive protein 2, HTAI2_HUMAN, HTATIP 2, HTATIP2, HTATIP2, Oxidoreductase HTATIP2, SDR44U1, Short chain dehydrogenase/reductase family 44U member 1, Tat interacting protein 30 kDa, Tat-interacting protein 30 kDa.

Background: Oxidoreductase required for tumor suppression. NAPDH-bound form inhibits nuclear import by competing with nuclear import substrates for binding to a subset of nuclear transport receptors. May act as a redox sensor linked to transcription through regulation of nuclear import. Isoform 1 is a metastasis suppressor with proapoptotic as well as antiangiogenic properties. Isoform 2 has an antiapoptotic effect.Tissue specificity: Ubiquitous. Highest level in liver. High levels in lung, skeletal muscle, pancreas and placenta. Moderate levels in heart and kidney. Low levels in brain.

Gene ID: 10553