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UBE2V1 antibody (AA 51-147)

UBE2V1 Reactivity: Human, Rat WB, ELISA, FACS, IF (cc), IF (p), IHC (fro), IHC (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN872599
  • Target See all UBE2V1 Antibodies
    UBE2V1 (Ubiquitin-Conjugating Enzyme E2 Variant 1 (UBE2V1))
    Binding Specificity
    • 15
    • 8
    • 6
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 51-147
    Reactivity
    • 47
    • 21
    • 19
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Rat
    Host
    • 44
    • 3
    Rabbit
    Clonality
    • 47
    Polyclonal
    Conjugate
    • 16
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This UBE2V1 antibody is un-conjugated
    Application
    • 35
    • 15
    • 13
    • 12
    • 12
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Cross-Reactivity
    Human, Rat
    Predicted Reactivity
    Mouse,Sheep,Pig,Horse,Chicken
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human UBE2V1
    Isotype
    IgG
    Top Product
    Discover our top product UBE2V1 Primary Antibody
  • Application Notes
    WB 1:300-5000
    ELISA 1:500-1000
    FCM 1:20-100
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Expiry Date
    12 months
  • Target
    UBE2V1 (Ubiquitin-Conjugating Enzyme E2 Variant 1 (UBE2V1))
    Alternative Name
    UBE2V1 (UBE2V1 Products)
    Synonyms
    CIR1 antibody, CROC-1 antibody, CROC1 antibody, UBE2V antibody, UEV-1 antibody, UEV1 antibody, UEV1A antibody, 0610011J09Rik antibody, AI256840 antibody, D7Bwg1382e antibody, CROC-1B antibody, ubiquitin conjugating enzyme E2 V1 antibody, ubiquitin-conjugating enzyme E2 variant 1 antibody, UBE2V1 antibody, ube2v1 antibody, Ube2v1 antibody
    Background

    Synonyms: CIR1, CROC-1, CROC1, CROC1A, TRAF6-regulated IKK activator 1 beta Uev1A, UB2V1_HUMAN, UBE2V 1, UBE2V, UBE2V1, Ubiquitin conjugating enzyme E2 variant 1, Ubiquitin-conjugating enzyme E2 variant 1, UEV-1, UEV1.

    Background: Has no ubiquitin ligase activity on its own. The UBE2V1-UBE2N heterodimer catalyzes the synthesis of non-canonical poly-ubiquitin chains that are linked through Lys-63. This type of poly-ubiquitination activates IKK and does not seem to involve protein degradation by the proteasome. Plays a role in the activation of NF-kappa-B mediated by IL1B, TNF, TRAF6 and TRAF2. Mediates transcriptional activation of target genes. Plays a role in the control of progress through the cell cycle and differentiation. Plays a role in the error-free DNA repair pathway and contributes to the survival of cells after DNA damage.

    Gene ID
    7335
    Pathways
    TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades
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