THAP1 antibody (AA 121-213)

Catalog No. ABIN872590

Product Details anti-THAP1 Antibody

Target: THAP1 (THAP Domain Containing, Apoptosis Associated Protein 1 (THAP1))

Binding Specificity: AA 121-213

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This THAP1 antibody is un-conjugated

Application: ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Sheep,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human THAP1

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for THAP1

Target: THAP1 (THAP Domain Containing, Apoptosis Associated Protein 1 (THAP1))

Alternative Name: THAP1 (THAP1 Products)

Synonyms: THAP1 antibody, thap1-a antibody, DYT6 antibody, 4833431A01Rik antibody, AW490810 antibody, zgc:136597 antibody, THAP domain containing, apoptosis associated protein 1 antibody, THAP domain containing 1 antibody, THAP domain containing, apoptosis associated protein 1 L homeolog antibody, thap1 antibody, THAP1 antibody, thap1.L antibody, Thap1 antibody

Background:

Synonyms: Nuclear proapoptotic factor, THAP 1, THAP domain containing apoptosis associated protein 1, THAP domain containing protein 1, THAP domain protein 1, THAP1_HUMAN.

Background: THAP1 contains a THAP domain, a zinc-dependent DNA-binding domain. It colocalizes with the apoptosis response protein PAWR/PAR-4 in promyelocytic leukemia (PML) nuclear bodies and is a pro-apoptopic protein that potentiates both serum-withdrawal and TNF-induced apoptosis. It is a physiologic regulator of endothelial cell proliferation and cell-cycle progression, two essential processes for angiogenesis.

Gene ID: 55145