COMMD3 antibody (AA 101-195)

Catalog No. ABIN872523

Product Details anti-COMMD3 Antibody

Target: COMMD3 (COMM Domain Containing 3 (COMMD3))

Binding Specificity: AA 101-195

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This COMMD3 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Dog,Cow

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human COMMD3

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for COMMD3

Target: COMMD3 (COMM Domain Containing 3 (COMMD3))

Alternative Name: Commd3 (COMMD3 Products)

Synonyms: zgc:103771 antibody, BUP antibody, C10orf8 antibody, AW550818 antibody, Bup antibody, D2Ertd542e antibody, COMM domain containing 3 antibody, COMM domain containing 3 L homeolog antibody, COMMD3 antibody, commd3 antibody, commd3.l antibody, Commd3 antibody

Background:

Synonyms: BUP, C10orf8, COMM domain-containing protein 3, Protein Bup, Protein PIL, COMMD3

Background: May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes (PubMed:21778237). May down-regulate activation of NF-kappa-B (PubMed:15799966). Modulates Na(+) transport in epithelial cells by regulation of apical cell surface expression of amiloride-sensitive sodium channel (ENaC) subunits (PubMed:23637203).

Gene ID: 23412

UniProt: Q9UBI1