ALOX5AP antibody (AA 65-161)

Catalog No. ABIN872471

Product Details anti-ALOX5AP Antibody

Target: ALOX5AP (Arachidonate 5-Lipoxygenase-Activating Protein (ALOX5AP))

Binding Specificity: AA 65-161

Reactivity: Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ALOX5AP antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Mouse, Rat

Predicted Reactivity: Human,Cow,Sheep,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human FLAP/5-lipoxygenase activating protein

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-ALOX5AP antibody (ABIN872471)

Elias, Ferré, Vilà, Muñoz, Casellas, Garcia, Molas, Agudo, Roca, Ruberte, Bosch, Franckhauser: "ALOX5AP Overexpression in Adipose Tissue Leads to LXA4 Production and Protection Against Diet-Induced Obesity and Insulin Resistance." in: Diabetes, Vol. 65, Issue 8, pp. 2139-50, (2016) (PubMed).

Target Details for ALOX5AP

Target: ALOX5AP (Arachidonate 5-Lipoxygenase-Activating Protein (ALOX5AP))

Alternative Name: 5-lipoxygenase activating protein (ALOX5AP Products)

Synonyms: fj65d02 antibody, zgc:63982 antibody, wu:fj65d02 antibody, flap antibody, al5ap antibody, Alox5ap antibody, ALOX5AP antibody, Flap antibody, FLAP antibody, arachidonate 5-lipoxygenase-activating protein antibody, arachidonate 5-lipoxygenase activating protein antibody, alox5ap antibody, ALOX5AP antibody, Alox5ap antibody

Background:

Synonyms: FLAP, Arachidonate 5-lipoxygenase-activating protein, MK-886-binding protein, ALOX5AP

Background: Required for leukotriene biosynthesis by ALOX5 (5-lipoxygenase). Anchors ALOX5 to the membrane. Binds arachidonic acid, and could play an essential role in the transfer of arachidonic acid to ALOX5. Binds to MK-886, a compound that blocks the biosynthesis of leukotrienes.

Gene ID: 241

UniProt: P20292