NEK1 antibody (AA 301-400)
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- Target See all NEK1 Antibodies
- NEK1 (NIMA-Related Kinase 1 (NEK1))
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Binding Specificity
- AA 301-400
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Reactivity
- Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This NEK1 antibody is un-conjugated
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Application
- ELISA, Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Cross-Reactivity
- Mouse, Rat
- Predicted Reactivity
- Human,Dog,Cow,Sheep,Rabbit
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human NEK1
- Isotype
- IgG
- Top Product
- Discover our top product NEK1 Primary Antibody
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- Application Notes
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Expiry Date
- 12 months
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Senataxin controls meiotic silencing through ATR activation and chromatin remodeling." in: Cell discovery, Vol. 1, pp. 15025, (2016) (PubMed).
: "
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Senataxin controls meiotic silencing through ATR activation and chromatin remodeling." in: Cell discovery, Vol. 1, pp. 15025, (2016) (PubMed).
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- Target
- NEK1 (NIMA-Related Kinase 1 (NEK1))
- Alternative Name
- NEK1 (NEK1 Products)
- Background
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Synonyms: SRPS2, SRTD6, SRPS2A, NY-REN-55, Serine/threonine-protein kinase Nek1, Never in mitosis A-related kinase 1, NimA-related protein kinase 1, Renal carcinoma antigen NY-REN-55, NEK1, KIAA1901
Background: Phosphorylates serines and threonines, but also appears to possess tyrosine kinase activity. Implicated in the control of meiosis (By similarity). Involved in cilium assembly. In response to injury that includes DNA damage, NEK1 phosphorylates VDAC1 to limit mitochondrial cell death.
- Gene ID
- 4750
- UniProt
- Q96PY6
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