TBCD antibody (AA 401-500)
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- Target See all TBCD Antibodies
- TBCD (Tubulin Folding Cofactor D (TBCD))
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Binding Specificity
- AA 401-500
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Reactivity
- Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This TBCD antibody is un-conjugated
- Application
- Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Cross-Reactivity
- Mouse
- Predicted Reactivity
- Human,Rat,Chicken,Rabbit
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human TBCD/Beta tubulin cofactor D
- Isotype
- IgG
- Top Product
- Discover our top product TBCD Primary Antibody
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- Application Notes
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Expiry Date
- 12 months
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- Target
- TBCD (Tubulin Folding Cofactor D (TBCD))
- Alternative Name
- Beta tubulin cofactor D (TBCD Products)
- Synonyms
- SSD-1 antibody, tfcD antibody, 2310057L06Rik antibody, A030005L14Rik antibody, mKIAA0988 antibody, tubulin folding cofactor D antibody, tubulin-specific chaperone d antibody, TBCD antibody, Tbcd antibody
- Background
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Synonyms: Beta tubulin cofactor D, Beta-tubulin cofactor D, KIAA0988, SSD 1, SSD-1, SSD1, tbcd, TBCD_HUMAN, tfcD, Tubulin folding cofactor D, Tubulin specic chaperone D, Tubulin-folding cofactor D, Tubulin-specic chaperone D.
Background: Tubulin-folding protein, involved in the first step of the tubulin folding pathway. Modulates microtubule dynamics by capturing GTP-bound beta-tubulin (TUBB). Acts as a GTPase-activating protein (GAP) for ARL2. Its ability to interact with beta tubulin is regulated via its interaction with ARL2. Induces microtubule disruption in absence of ARL2. Increases degradation of beta tubulin, when overexpressed in polarized cells. Promotes epithelial cell detachment, a process antagonized by ARL2. Induces tight adherens and tight junctions disassembly at the lateral cell membrane.
- Gene ID
- 6904
- Pathways
- Cell-Cell Junction Organization
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