TIAF1 antibody (AA 34-115)

Catalog No. ABIN872387

Product Details anti-TIAF1 Antibody

Target: TIAF1 (TGFB1-Induced Anti-Apoptotic Factor 1 (TIAF1))

Binding Specificity: AA 34-115

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TIAF1 antibody is un-conjugated

Application: ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human TIAF1

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for TIAF1

Target: TIAF1 (TGFB1-Induced Anti-Apoptotic Factor 1 (TIAF1))

Alternative Name: TIAF1 (TIAF1 Products)

Synonyms: myo18l1 antibody, tiaf1 antibody, wu:fb52c07 antibody, MAJN antibody, SPR210 antibody, myosin XVIIIAb antibody, TGFB1-induced anti-apoptotic factor 1 antibody, myo18ab antibody, TIAF1 antibody

Background:

Synonyms: MAJN, TGFB1 induced anti apoptotic factor 1 12 kDa TGF beta1 induced antiapoptotic factor, TGFB1 induced anti apoptotic factor 1, TIAF1_HUMAN.

Background: TIAF-1 (TGF Beta 1-induced antiapoptotic factor 1), also known as MYO18A, MAJN or MYSPDZ, is a TGF Beta 1-induced anti-apoptotic factor that localizes to the nucleus and functions to inhibit the cytotoxic effects of TNF? TRADD and FADD. Two isoforms of mouse TIAF-1 exist and are designated MysPDZ-Alpha and MysPDZ-Beta. MysPDZ-Alpha consists of a KE-rich region, an N-terminal PDZ domain and a prevalent myosin homologous head region, while the MysPDZ-Beta isoform lacks the KE-rich region and PDZ domain. MysPDZ-Alpha is present in most tissues and is known to co-localize with the ER-Golgi complex and with membrane ruffles and filopodia. MysPDZ-Beta is expressed specifically in hematopoietic tissues and cell lines and shows dispersed localization in the cytoplasm.

Gene ID: 9220