OSBPL8 antibody (AA 121-220)

Catalog No. ABIN872318

Product Details anti-OSBPL8 Antibody

Target: OSBPL8 (Oxysterol Binding Protein-Like 8 (OSBPL8))

Binding Specificity: AA 121-220

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This OSBPL8 antibody is un-conjugated

Application: ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ORP8

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for OSBPL8

Target: OSBPL8 (Oxysterol Binding Protein-Like 8 (OSBPL8))

Alternative Name: Orp8 (OSBPL8 Products)

Synonyms: RGD1561474 antibody, DKFZp469P0923 antibody, MST120 antibody, MSTP120 antibody, ORP8 antibody, OSBP10 antibody, AA536976 antibody, AA536995 antibody, C730029P18Rik antibody, D330025H14Rik antibody, ORP-8 antibody, oxysterol binding protein-like 8 antibody, oxysterol binding protein like 8 antibody, oxysterol binding protein like 8 L homeolog antibody, oxysterol-binding protein-related protein 8 antibody, Osbpl8 antibody, OSBPL8 antibody, osbpl8.L antibody, osbpl8 antibody, LOC100175952 antibody

Background:

Synonyms: MST120, MSTP120, ORP 8, OSBP related protein 8, OSBP10, OSBPL8, Oxysterol binding protein like 8, Oxysterol binding protein like protein 8, Oxysterol binding protein related protein 8, OSBL8_HUMAN.

Background: ORP8 is a member of the oxysterol-binding protein related protein family. In humans, the gene family consists of 12 members, and extensive splice variation increases the number of encoded protein products substantially. The ORPs have been implicated as sterol sensors that regulate a number of cellular functions including sterol and neutral lipid metabolism, intracellular lipid transport, membrane trafficking and cell signaling. ORP8 has been recently shown to act as a sterol sensor that affects the reverse cholesterol transport process via modulation of ABCA1 expression and macrophage cholesterol efflux.

Gene ID: 114882