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TRKB antibody (AA 703-707)
NTRK2
Reactivity: Human, Rat, Mouse
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-TRKB Antibody
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Target
See all TRKB (NTRK2) Antibodies
TRKB (NTRK2)
(Neurotrophic Tyrosine Kinase, Receptor, Type 2 (NTRK2))
Binding Specificity
All epitopes for TRKB antibodies
AA 703-707
Reactivity
All reactivities for TRKB antibodies
Human, Rat, Mouse
Host
All hosts for TRKB antibodies
Rabbit
Clonality
All clonalities for TRKB antibodies
Polyclonal
Conjugate
All conjugates for TRKB antibodies
This TRKB antibody is un-conjugated
Application
All applications for TRKB antibodies
Western Blotting (WB)
Specificity
The antibody detects endogenous levels of total TrkB protein.
Purification
Affinity purified
Immunogen
Peptide sequence around AA 703-707 (T-D-Y -Y-R) derived from TrkB Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.
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Discover our top product NTRK2 Primary Antibody
Alternatives
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anti-Neurotrophic Tyrosine Kinase, Receptor, Type 2 (NTRK2) (AA 57-70), (Extracellular Domain) antibody
NTRK2
Reactivity: Human, Rat, Mouse
WB, IHC, IF, FACS, ICC, LCI
Host: Rabbit
Polyclonal
unconjugated
Application Details
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Application Notes
Western blotting: 1:500-1:1000
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
1 mg/mL
Buffer
Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C/-20 °C
Storage Comment
Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
References for anti-TRKB antibody (ABIN871618)
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Li, Liu : "The novel squamosamide derivative FLZ enhances BDNF/TrkB/CREB signaling and inhibits neuronal apoptosis in APP/PS1 mice. " in: Acta pharmacologica Sinica , Vol. 31 , Issue 3 , pp. 265-72 , (2010 ) (PubMed ).
Target Details for TRKB
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Target
TRKB (NTRK2)
(Neurotrophic Tyrosine Kinase, Receptor, Type 2 (NTRK2))
Alternative Name
TrkB (NTRK2 Products )
Synonyms
trkb antibody, trkb-b antibody, xtrkb antibody, si:ch211-220b11.1 antibody, trkB2 antibody, NTRK2 antibody, ntrk2 antibody, gp145-trkb antibody, TRKB antibody, GP145-TrkB antibody, trk-B antibody, AI848316 antibody, C030027L06Rik antibody, Tkrb antibody, trkB antibody, RATTRKB1 antibody, TRKB1 antibody, Trk-B antibody, TrkB antibody, neurotrophic receptor tyrosine kinase 2 antibody, neurotrophic receptor tyrosine kinase 2 L homeolog antibody, neurotrophic tyrosine kinase, receptor, type 2b antibody, neurotrophic receptor tyrosine kinase 2 S homeolog antibody, neurotrophic tyrosine kinase, receptor, type 2 antibody, NTRK2 antibody, ntrk2.L antibody, ntrk2b antibody, ntrk2.S antibody, ntrk2 antibody, Ntrk2 antibody
Background
Receptor for brain-derived neurotrophic factor (BDNF), neurotrophin-3 and neurotrophin-4/5 but not nerve growth factor (NGF). Involved in the development and/or maintenance of the nervous system. This is a tyrosine-protein kinase receptor. Known substrates for the TRK receptors are SHC1, PI-3 kinase, and PLC-gamma-1.
Molecular Weight
145 kDa
Gene ID
4915
NCBI Accession
NP_001007
UniProt
Q16620
Pathways
RTK Signaling , Neurotrophin Signaling Pathway , cAMP Metabolic Process , Skeletal Muscle Fiber Development , Feeding Behaviour , Dicarboxylic Acid Transport
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