SUFUH antibody (pSer342)
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- Target See all SUFUH Antibodies
- SUFUH (Suppressor of Fused Homolog (SUFUH))
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Binding Specificity
- pSer342
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This SUFUH antibody is un-conjugated
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Application
- Western Blotting (WB)
- Specificity
- The antibody detects endogenous level of Sufu protein only when phosphorylated at serine 342.
- Purification
- Affinity purified
- Immunogen
- Peptide sequence around phosphorylation site of pSer342 (A-P-S (p) -R-K) derived from Human Sufu. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.
- Top Product
- Discover our top product SUFUH Primary Antibody
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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Dual Phosphorylation of suppressor of fused (Sufu) by PKA and GSK3beta regulates its stability and localization in the primary cilium." in: The Journal of biological chemistry, Vol. 286, Issue 15, pp. 13502-11, (2011) (PubMed).
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Dual Phosphorylation of suppressor of fused (Sufu) by PKA and GSK3beta regulates its stability and localization in the primary cilium." in: The Journal of biological chemistry, Vol. 286, Issue 15, pp. 13502-11, (2011) (PubMed).
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- Target
- SUFUH (Suppressor of Fused Homolog (SUFUH))
- Alternative Name
- Sufu (SUFUH Products)
- Synonyms
- CG6054 antibody, Dmel\\CG6054 antibody, SU(FU) antibody, SUFU antibody, Su(Fu) antibody, SuFu antibody, Sufu antibody, su(fu) antibody, sufu antibody, Xsufu antibody, sufuh antibody, sufuxl antibody, PRO1280 antibody, SUFUH antibody, SUFUXL antibody, Su(fu) antibody, dre antibody, fi39e05 antibody, wu:fi39e05 antibody, 2810026F04Rik antibody, b2b273Clo antibody, Suppressor of fused antibody, SUFU negative regulator of hedgehog signaling L homeolog antibody, SUFU negative regulator of hedgehog signaling antibody, suppressor of fused homolog (Drosophila) antibody, Su(fu) antibody, sufu.L antibody, SUFU antibody, sufu antibody, Sufu antibody
- Background
- SUFU encodes a component of the Sonic hedgehog (SHH, MIM 600725)/Patched (PTCH, MIM 601309) signaling pathway. Mutations in genes encoding components of this pathway are deleterious for normal development and are associated with cancer-predisposing syndromes (e.g., HPE3, MIM 142945, BCNS, MIM 109400, and GCPS, MIM 175700)
- Molecular Weight
- 54 kDa
- Gene ID
- 51684
- NCBI Accession
- NP_057253
- UniProt
- Q9UMX1
- Pathways
- Hedgehog Signaling, Tube Formation, Maintenance of Protein Location
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