KCNT1 antibody (AA 1168-1237)

Catalog No. ABIN863116

Product Details anti-KCNT1 Antibody

Target: KCNT1 (Potassium Channel, Subfamily T, Member 1 (KCNT1))

Binding Specificity: AA 1168-1237

Reactivity: Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This KCNT1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), Antibody Array (AA)

Specificity: Detects ~140 kDa. Weak human detection. Does not cross-react with KCNT2/Slo2.1/Slick.

Cross-Reactivity: Human, Mouse, Rat

Purification: Protein G Purified

Immunogen: Fusion protein amino acids 1168-1237 of rat Slo2.2 (Slack)

Clone: N3-26 (Formerly S3-26)

Isotype: IgG1

Application Details

Application Notes:

• WB (1:1000)
• IHC (1:1000)
• ICC/IF (1:100)
• optimal dilutions for assays should be determined by the user.

Comment:

1 μg/ml of ABIN863116 was sufficient for detection of Slo2.2 in 10 μg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: -20°C

Target Details for KCNT1

Target: KCNT1 (Potassium Channel, Subfamily T, Member 1 (KCNT1))

Alternative Name: Slo2.2 (KCNT1 Products)

Synonyms: EIEE14 antibody, ENFL5 antibody, KCa4.1 antibody, SLACK antibody, bA100C15.2 antibody, Slack antibody, rSlo2 antibody, C030030G16Rik antibody, mKIAA1422 antibody, slo2 antibody, slack antibody, Slo2.2 antibody, MGC146594 antibody, potassium sodium-activated channel subfamily T member 1 antibody, potassium channel subfamily T member 1 antibody, potassium channel, subfamily T, member 1 antibody, potassium channel, sodium activated subfamily T, member 1 antibody, KCNT1 antibody, LOC100436526 antibody, Kcnt1 antibody, kcnt1 antibody

Background: Slo2.2 is a novel member of the mammalian Slo potassium channel gene family. Slo2 channels may contribute to the resting potentials of cells that control their basal level of excitability (1). They also have sensors that couple channel activity to the intracellular concentrations of Na+ and Cl- (2).

Gene ID: 60444

NCBI Accession: NP_068625

UniProt: Q9Z258