FANCG antibody (pSer383) (Biotin)

Catalog No. ABIN800810

Product Details anti-FANCG Antibody (Biotin)

Target: FANCG (Fanconi Anemia Complementation Group G (FANCG))

Binding Specificity: pSer383

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FANCG antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Predicted Reactivity: Human,Mouse,Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human FANCG around the phosphorylation site of Ser383

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for FANCG

Target: FANCG (Fanconi Anemia Complementation Group G (FANCG))

Alternative Name: FANCG (FANCG Products)

Synonyms: xFANCG antibody, FAG antibody, XRCC9 antibody, AU041407 antibody, Xrcc9 antibody, Fanconi anemia complementation group G S homeolog antibody, Fanconi anemia complementation group G antibody, Fanconi anemia, complementation group G antibody, fancg.S antibody, FANCG antibody, Fancg antibody

Background:

Synonyms: FANCG phospho S383, p-FANCG phospho S383, DNA repair protein XRCC9, DNA-repair protein XRCC9, FAG, Fanconi anaemia complementation group G, Protein FACG, X ray repair, complementing defective, in Chinese hamster cells 9, XRCC9.

Background: FANCG, involved in Fanconi anemia, confers resistance to both hygromycin and mitomycin C. FANCG contains a 5-prime GC-rich untranslated region characteristic of housekeeping genes. The putative 622-amino acid protein has a leucine-zipper motif at its N-terminus. Fanconi anemia is an autosomal recessive disorder with diverse clinical symptoms, including developmental anomalies, bone marrow failure, and early occurrence of malignancies. A minimum of 8 FA genes have been identified.

Gene ID: 2189

Pathways: DNA Damage Repair