ECT2 antibody (pThr373) (Biotin)

Catalog No. ABIN800690

Product Details anti-ECT2 Antibody (Biotin)

Target: ECT2 (Epithelial Cell Transforming Sequence 2 Oncogene (ECT2))

Binding Specificity: pThr373

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ECT2 antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Predicted Reactivity: Human,Dog,Cow,Sheep

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human ECT2 around the phosphorylation site of Thr373

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for ECT2

Target: ECT2 (Epithelial Cell Transforming Sequence 2 Oncogene (ECT2))

Alternative Name: ECT2 (ECT2 Products)

Synonyms: ECT2 antibody, arhgef31 antibody, xect2 antibody, AI528536 antibody, mKIAA4037 antibody, ARHGEF31 antibody, ect2 antibody, epithelial cell transforming 2 antibody, ect2 oncogene antibody, epithelial cell transforming 2 S homeolog antibody, ECT2 antibody, ect2 antibody, Ect2 antibody, ect2.S antibody

Background:

Synonyms: ECT2 phospho T373, ECT2 phospho Thr373, p-ECT2 Thr373, ECT 2, ECT2, ECT-2, ECT2 protein, Epithelial cell transforming sequence 2, Epithelial cell transforming sequence 2 oncogene, Epithelial cell transforming sequence 2 oncogene protein, FLJ10461, MGC138291, Protein ECT2, ECT2_HUMAN, Epithelial cell-transforming sequence 2 oncogene.

Background: The protein encoded by this gene is a transforming protein that is related to Rho-specific exchange factors and yeast cell cycle regulators. The expression of this gene is elevated with the onset of DNA synthesis and remains elevated during G2 and M phases. In situ hybridization analysis showed that expression is at a high level in cells undergoing mitosis in regenerating liver. Thus, this protein is expressed in a cell cycle-dependent manner during liver regeneration, and is thought to have an important role in the regulation of cytokinesis. [provided by RefSeq].

Gene ID: 1894

Pathways: Neurotrophin Signaling Pathway, Cell-Cell Junction Organization