Huntingtin antibody (AA 2703-2911)
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- Target See all Huntingtin (HTT) Antibodies
- Huntingtin (HTT)
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Binding Specificity
- AA 2703-2911
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Reactivity
- Human, Rabbit
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This Huntingtin antibody is un-conjugated
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Application
- Immunohistochemistry (IHC), Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Brand
- IHC-plus™
- Specificity
- Reacts with an epitope corresponding to the human HDC region (2703-2911 amino acids) of the huntingtin protein. Detects a 350kD band on Western Blots but also detects smaller degradation products of Huntingtin. Recognizes both denatured and native Huntingtin in human brain.
- Purification
- Protein G purified
- Immunogen
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Recombinant protein corresponding to amino acids 2703 - 2911 of huntingtin.
Type of Immunogen: Recombinant protein - Isotype
- IgG1
- Top Product
- Discover our top product HTT Primary Antibody
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- Application Notes
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Approved: IHC, IHC-Fr, IHC-P (10 μg/mL), IP, WB
Usage: Suitable for use in Immunohistochemistry, Immunoprecipitation and Western Blot. Immunohistochemistry: Frozen, FFPE (human). Increased cytoplasmic staining, relative to nuclear, has been reported using formaldehyde as a fixative compared with acetone/methanol. Positive control: IHC frozen-rabbit btain. - Comment
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Target Species of Antibody: Human
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- PBS, 0.09 % sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid freeze-thaw cycles.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
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- Target
- Huntingtin (HTT)
- Alternative Name
- HTT / Huntingtin (HTT Products)
- Background
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Name/Gene ID: HTT
Family: Hungtintin
Synonyms: HTT, Huntingtin, Huntington disease protein, IT15, HD, HD protein - Gene ID
- 3064
- UniProt
- P42858
- Pathways
- PI3K-Akt Signaling, Hormone Transport, Transition Metal Ion Homeostasis, Tube Formation, Protein targeting to Nucleus, Dicarboxylic Acid Transport
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