Glutamate Receptor 3 antibody (N-Term)

Catalog No. ABIN790676

Product Details anti-Glutamate Receptor 3 Antibody

Target: Glutamate Receptor 3 (GRIA3) (Glutamate Receptor, Ionotropic, AMPA 3 (GRIA3))

Binding Specificity: N-Term

Reactivity: Human, Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This Glutamate Receptor 3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Brand: IHC-plus™

Specificity: Recognizes the ~98kD Glutamate Receptor 3 (GluR3), and demonstrates no reactivity with cells transfected with GluR1, GluR2, or GluR4. Reactivity has been confirmed with HEK293 cells transfected with AMPA GluR cDNAs as well as human, rat, and macaque monkey brain extracts by Western Blot and rat hippocampus by immunofluorescence, immunocytochemistry, and immunogold labeling/electron microscopy.

Purification: Protein A purified

Immunogen: Fusion protein encompassing the N-terminal region of rat GluR3.

Type of Immunogen: Fusion protein

Isotype: IgG1

Application Details

Application Notes: Approved: ICC (1 - 3 μg/mL), IF (1 - 3 μg/mL), IHC, IHC-P (20 μg/mL), WB (5 μg/mL)

Usage: Suitable for use in Western Blot, Immunocytochemistry, Immunohistochemistry (human FFPE), Immunofluorescence and Electron Microscopy. Recommended Dilution: Western Blot: 5 μg/mL. Immunocytochemistry: 1-3 μg/mL. Immunofluorescence with rat brains: 1-3 μg/mL. Immunogold labeling/Electron Microscopy: 1-3 μg/mL.

Comment:

Target Species of Antibody: Rat

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.4, 0.1 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: avoid freeze thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Short term 4°C, long term aliquot and store at -20°C, avoid freeze-thaw cycles.

Target Details for Glutamate Receptor 3

Target: Glutamate Receptor 3 (GRIA3) (Glutamate Receptor, Ionotropic, AMPA 3 (GRIA3))

Alternative Name: GRIA3 / GLUR3 (GRIA3 Products)

Background: Name/Gene ID: GRIA3
Subfamily: Glutamate receptor - ionotropic (NMDA receptor)
Family: Ion Channel

Synonyms: GRIA3, AMPA 3, Glutamate receptor 3, Glutamate receptor C, GLUR-C, GLUR3, GLURC, Glutamate receptor subunit 3, DJ1171F9.1, GluA3, GluR-3, GLUR-K3, MRX94

Gene ID: 2892

UniProt: P42263

Pathways: PI3K-Akt Signaling, cAMP Metabolic Process, Synaptic Membrane