Cathepsin L2 antibody (Internal Region)

Catalog No. ABIN784595

Product Details anti-Cathepsin L2 Antibody

Target: Cathepsin L2 (CTSL2)

Binding Specificity: Internal Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cathepsin L2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificity: This antibody detects endogenous levels of of fragment of activated CATL2 resulting from cleavage adjacent to Leu114.

Purification: Immunoaffinity Chromatography

Immunogen: Synthetic peptide from human CATL2. Remarks: Antigen Modification: Internal

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS (without Mg2+, Ca2+), pH 7.4, 150 mM Sodium Chloride, 0.02 % Sodium Azide and 50 % Glycerol

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store the antibody (in aliquots) at -20 °C or lower. Avoid freeze-thaw cycles.

Target Details for Cathepsin L2

Target: Cathepsin L2 (CTSL2)

Alternative Name: Cathepsin L2 (CTSL2 Products)

Synonyms: CATL2 antibody, CTSL2 antibody, CTSU antibody, CTSL antibody, CTSL1 antibody, ctsl2 antibody, LOC100232421 antibody, cathepsin V antibody, cathepsin V L homeolog antibody, cathepsin L antibody, CTSV antibody, ctsv.L antibody, ctsv antibody, CTSL antibody, Ctsv antibody

Background: Cathepsin V, also known as Cathepsin L2 and Cathepsin U, is a cysteine protease of the papain family. It is expressed as a proenzyme in lysosomes, which can be autocatalytically converted to the mature form at pH 4.0. Cathepsin V is specifically expressed in the thymus, testis, and corneal epithelium.Synonyms: CATL2, CTSL2, CTSU, CTSV, Cathepsin U, Cathepsin V

Gene ID: 1515

NCBI Accession: NP_001188504

Pathways: Toll-Like Receptors Cascades