Fascin 2 antibody (Internal Region)
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- Target See all Fascin 2 (FSCN2) Antibodies
- Fascin 2 (FSCN2)
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Binding Specificity
- Internal Region
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Reactivity
- Human, Mouse, Rat, Dog
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Host
- Goat
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Clonality
- Polyclonal
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Conjugate
- This Fascin 2 antibody is un-conjugated
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Application
- Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
- Sequence
- CHHRGSNQLD TNR
- Specificity
- This antibody is expected to recognize both reported isoforms (NP_001070650.1 and NP_036550.1).
- Cross-Reactivity (Details)
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Species reactivity (expected):Mouse, Rat, Dog.
Species reactivity (tested):Human. - Purification
- Affinity Chromatgraphy
- Immunogen
- Peptide with sequence from the internal region of the protein sequence according to NP_001070650.1, NP_036550.1. Genename: FSCN2
- Top Product
- Discover our top product FSCN2 Primary Antibody
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Concentration
- 0.5 mg/mL
- Buffer
- Tris saline, pH ~7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Target
- Fascin 2 (FSCN2)
- Alternative Name
- Fascin-2 (FSCN2 Products)
- Synonyms
- fascin-2 antibody, A930022G03 antibody, C630046B20Rik antibody, ahl8 antibody, RFSN antibody, RP30 antibody, fascin actin-bundling protein 2, retinal antibody, fascin actin-bundling protein 1 antibody, fascin actin-bundling protein 2 antibody, FSCN2 antibody, FSCN1 antibody, Fscn2 antibody
- Background
- Fascin-2 Acts as an actin bundling protein. May play a pivotal role in photoreceptor cell-specific events, such as disk morphogenesis. Defects in FSCN2 are the cause of retinitis pigmentosa type 30 (RP30) [MIM:607921]. RP leads to degeneration of retinal photoreceptor cells. Patients typically have night vision blindness and loss of midperipheral visual field. As their condition progresses, they lose their far peripheral visual field and eventually central vision as well. RP30 inheritance is autosomal dominant.Synonyms: FSCN2, Retinal fascin
- Gene ID
- 25794
- NCBI Accession
- NP_001070650
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