4933419D20Rik antibody, AA986696 antibody, BIGM103 antibody, Zip8 antibody, LZT-Hs6 antibody, ZIP8 antibody, solute carrier family 39 (metal ion transporter), member 8 antibody, solute carrier family 39 member 8 antibody, Slc39a8 antibody, SLC39A8 antibody
Background
The zinc transporter ZIP8, also known as SLC39A9, is a member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. The zinc transporter family is divided into four subfamilies (I, II, LIV-1 and gufA). ZIP8 is glycosylated and located at the plasma membrane and mitochondria. It has been identified as the transporter responsible for transport of the toxic Cadmium cation. ZIP8 has also been suggested to play a role in the regulation of interferon-gamma expression in activated human T cells.Synonyms: BCG-induced integral membrane protein in monocyte clone 103 protein, BIGM103, LIV-1 subfamily of ZIP zinc transporter 6, LZT-Hs6, Solute carrier family 39 member 8, ZIP-8, ZIP8, Zrt- and Irt-like protein 8