EFCAB4A antibody (Center)

Catalog No. ABIN783783

Product Details anti-EFCAB4A Antibody

Target: EFCAB4A (EF-Hand Calcium Binding Domain 4A (EFCAB4A))

Binding Specificity: Center

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EFCAB4A antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody detects EFCAB4A at Center.

Cross-Reactivity (Details): Species reactivity (tested):Human, mouse, rat

Purification: Affinity chromatography purified via peptide column

Immunogen: 15 amino acid peptide near the center of human EFCAB4A

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: PBS containing 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.

Target Details for EFCAB4A

Target: EFCAB4A (EF-Hand Calcium Binding Domain 4A (EFCAB4A))

Alternative Name: EFCAB4A (EFCAB4A Products)

Synonyms: CRACR2B antibody, 6330520A15Rik antibody, BC026645 antibody, Cracr2a antibody, Efcab4 antibody, RGD1560911 antibody, zgc:158448 antibody, calcium release activated channel regulator 2B antibody, cracr2b antibody, CRACR2B antibody, Cracr2b antibody

Background: EFCAB4A, also known as Calcium release-activated calcium channel regulator 2B, is a novel Ca2+-binding EF-hand protein that is thought to play a key role in store-operated Ca2+ entry in T-cells by regulating CRAC channel activation, but the detailed function is still under investigation. It is likely to play a similar role as the related protein EFCAB4B, which acts as a cytoplasmic calcium-sensor that forms a complex with ORAI1 and STIM1 at the junctional regions between the plasma membrane and the endoplasmic reticulum upon low Ca2+ concentration.Synonyms: EF-hand calcium-binding domain-containing protein 4A

Gene ID: 283229

NCBI Accession: NP_775855

UniProt: Q8N4Y2